The original BB by Victor Fox Publications, who was a policeman by day. A scientist friend would produce and provide him with a drug similar to Miraclo, called Vitamin 2X. I do not remember if the effects lasted one day or more. I am not sure if this character is owned by DC, he seems a bit forgotten by time. Also, the scientist in the comic book went by one name. The same BB in a newspaper strip of that day had a differently named scientist provide him with the drug.

http://en.wikipedia.org/wiki/Blue_Beetle

Eventually this Blue Beetle would be replaced by Blue Beetle II, an archeologist who found a magical gem, the Egyptian blue scarab. This is a character that DC has used, and other companies as well, even thought they do not use the name Blue Beetle (see Dynamite Comics).

Then this BB was replaced by Blue Beetle III- the Ditko one – for Charlton comics- who was an acrobat, and brilliant technician. This character was purchased by DC. He was killed off. He inspired the character Nite Owl of the Watchmen series.

Not too long ago DC comics created a new BB: Blue Beetle IV, a teen who has come into the possession of the magical scarab, which now has been changed into a hyper science object of alien origins.

Probably more than what you wanted to know.

I thought that a similarity could be found between the 2 chemicals. And I think that Blue Beetle I was created before Hour-Man (as he was known back at the beginning).

A derivative of the Super-Soldier Serum transformed Frieda Ratsel into Warrior Woman, an enemy of the Invaders in World War II (or at least Roy Thomas’s Marvel version thereof). Contrary to some accounts, Master Man and his various successors — Axl Nacht/Gottskrieger and the Master Race skinheads from Brubaker’s Cap — are products of a Nazi effort to replicate the serum sans notes, which may mean there’s no real resemblance.

Serum SO-4, which created the Man-Thing, the second Glob (Sumner Beckwith), and the creatures of Project: Glamor was an effort to recreate and refine the original Serum, but one that was also being worked on without access to the original SSS and which had been modified to try to mutate human beings into creatures capable of surviving a pollution-driven ecological shift.

The Burstein Process, which empowered Warhawk in its early form, then Luke Cage, John Bushmaster, Cruz Bushmaster, and several others; and whose refined version was the true source of the Anti-Cap/Super-Sailor’s abilities, is a different process entirely.

Likewise, the Power Broker process that gave U.S. Agent, Battlestar, and scores of Marvel Universe pro wrestlers (including the Grapplers) their strength appears to be a very different process developed by Dr. Karl Malus. For one thing, it doesn’t appear to use any chemical components, just some sort of mutagenic rays. And the super-soldier Nuke has been revealed as a Weapon Plus/Weapon X creation, one involving cybernetics as well as pharmacological enhancements.

Finally, there’s the recent creation MVP and his various clones (long story), who received no pharmacological or mutagenic treatment at all. Rather, the creator of the original Super-Soldier Serum, Abraham Erskine, had apparently developed a dietetic and physical program that could achieve similar effects if followed from birth by a normal human. (Shades of Doc Samson!)

In any case, it’s still not entirely clear how the SSS works, unlike Venom, which is essentially an instantaneously-acting anabolic steroid. Apparently the SSS induces permanent mutations and has a retroviral component, but this retrovirus is not the whole process. Quite what the Vita-Rays are or even do to the Serum is unclear too, though missing the Vita treatment results in superhuman strength along with rapid-onset organic dementia which initially presents with symptoms of both paranoid schizophrenia and borderline personality disorder. (Jack Monroe is the only person we’ve seen go through the whole series of symptoms of the Serum sans Vita-Rays; he went from the super-strong paranoid symptoms to, at the end of his life and after an alleged “cure” which didn’t entirely take, full-blown dementia with hallucinations and serious memory problems. And in between he’d been brainwashed with nanotechnology, which was likely a complicating factor.)

And perhaps you can track the Legacy Virus, or have you?

-Aine