Apothecarius Argentum was a manga published by DC imprint CMX. The story takes place primarily in the quasi-medieval kingdom of Beazol and features the Princess Primula and her Royal Apothecary, Argent.
Argent is something of a contradiction, being both a Basilisk and an apothecary. An apothecary is simply another name for a physician. Basilisks are rare individuals who were fed increasing doses of various toxins as children until they became immune to all poisons. Unfortunately, this process turns the Basilisks themselves toxic to anyone who touches them. Thus Argent is both a healer and a killer.
The initial volumes of the story took place in Beazol, but later volumes have had the characters travel to other countries. Recently, Argent has traveled to Castoria, looking for a fabled gem that is said to cure a Basilisk of their toxic nature.
Plot Synopsis:
Argent and his assistant Soda remain in the distant nation of Castoria, apprenticed to the brilliant but cranky healer Lulu. A local girl named Popola is staying with them as well. As this volume starts, Lulu and Argent are pulling an infected tooth in a reluctant patient. A lengthy debate on the ethics of abortion follows, then an emergency c-section. After than, they foil the efforts of Zendor, a local merchant who is consorting with Caduceus, the evil organization that creates and sells Basilisks. Zendor is selling babies to Caduceus, as well as the ingredients necessary to make gunpowder and bullets. Argent, Soda, Popola, and Lulu save the babies, stop Zendor, and drive Caduceus away – at least for now. Argent finally learns the secret of the Basilisk cure and, at the end of the volume, he and Soda return to their home country of Beazol.
Most of the medical scenes are found in the first third of the book; the last two thirds contain stories focusing on political maneuvering and rescue missions.
1. Anesthetics
The anesthetic used by Lulu for the dental extraction mad is made by “mixing minerals or metal with nitric acid.” She also mentions that some people “deliberately inhaled the fumes to become intoxicated.” What she is describing in Nitrous Oxide (i.e. laughing gas). Traditionally, it was produced by pouring nitric acid over iron filings. It can be used as an intoxicant – in fact it was used in such a way long before its anesthetic properties were discovered.
She mentions another anesthetic gas that is both stronger and more dangerous than nitrous oxide. This could be either chloroform or ether (she’s probably referring to ether, as that was mentioned in the previous volume).
2. Claviceps
Lulu keeps some moldy rye, which she tells Argent she uses to treat migraines. This mold is the fungus Claviceps pupurea, which contains the potent chemical ergotamine. Until about twenty years ago, ergotamine was the primary treatment for severe migraines. While it is still used a little today, most migraine patients now take the safer and more reliable Triptan drugs (Imitrex, Zolmig, Maxalt, etc.). Ergotamine can also cause uterine contractions, and has been used since the Middle Ages to induce abortions. For this reason, it is a Category X drug, and should not be taken during pregnancy.
3. Placental Abruption
An abruption occurs when the placenta pulls away from the wall of the uterus. This can be life threatening to both mother and child. The placenta is literally the lifeline for the baby, so if it is injured in any way, the baby’s life is at risk. An abruption can also cause a severe hemorrhage and lead to the mother bleeding to death. Mild abruptions can be treated with bed rest and observation, but severe cases require an immediate caesarean section.
Previous Apothercarius Argentum annotations
Other manga medical annotations